Request PDF on ResearchGate | Intérêt des acides biliaires dans la cholestase gravidique | Intrahepatic cholestasis during pregnancy is a risk factor for. La cholestase gravidique a été reliée à des critères de jugement maternels et fœtaux/néonatals indésirables. Du fait que la physiopathologie est mal comprise, . Interventions pour le traitement de la cholestase gravidique. This is not the most recent version of this Review. view the current version 24 June

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Hépato-Gastro & Oncologie Digestive

The susceptibility is explained by polymorphisms of genes encoding hepatocytic transport proteins that are important for bile secretion. Top of the page – Article Outline.

gravidiqu The disease is probably due to susceptibility to estrogens and progesterone, whose serum concentration is elevated during pregnancy and which are cholestatic. Bile acids, Ursodeoxycholic acid, Prematurity, Pruritus. As per the Law relating to information storage and personal integrity, you have the right to oppose art 26 of that lawaccess art 34 of that law and rectify art 36 of that law your personal data.


La cholestase gravidique – EM|consulte

It occurs during the second or third trimester. It is slightly more frequent during twin pregnancies. If you are a subscriber, please sign in ‘My Account’ at the top right of the screen.

Its prevalence in France is of the order of 1 per pregnancies.

Personal information regarding our website’s visitors, including their gragidique, is confidential. Contact Help Who are we? Cholestasis of pregnancy presents with pruritus, sometimes incapacitating, less frequently by jaundice.

La cholestase gravidique Intrahepatic cholestasis of pregnancy. Gravity of the disease comes from the occurrence of fetal complications, in particular prematurity often induced by obstetrical teams and its pulmonary complications, and sudden intra-uterine fetal death. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.


The owners of this website hereby guarantee to chopestase the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties. Journal page Archives Contents list. Liver tests are abnormal, with mainly an increase in serum transaminases and bile acids.


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Clinical signs and biochemical abnormalities normalize rapidly after delivery, at most after 3 to 4 weeks. Treatment by the bile acid ursodeoxycholic acid improves pruritus and decreases the frequency of fetal complications, without side effects in the mother or baby. Access to the text HTML. In forms with severe pruritus, early delivery by induced labor between 37 and 38 weeks may be necessary.

Elle survient pendant le 2 e ou le 3 e trimestre de la grossesse.

Outline Masquer le plan. You cohlestase move this window by clicking on the headline. Besides disturbing pruritus, maternal prognosis is good. If you want to subscribe to this journal, see our rates You can purchase this item in Pay Per View: Access to the full text of this article requires a subscription.