con el diagnóstico histopatológico de cordoma de la base del cráneo .. magnética cerebral, corte sagital, secuencia T1, cordoma del clivus. Resección endoscópica de cordoma del clivus. Descripción de un chordoma; clivus; endoscopic resection; malignant tumor. RESUMEN. Download Citation on ResearchGate | On Dec 19, , Ines Gamboa and others published Resección endoscópica de cordoma del clivus. Descripción de un.

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Additionally, it represents an example of intraspinal extraosseous chordoma, a lesion not previously described. Some authors 14 reported that the surgically total excision was goal of treatment because the intradural chordomas had slower growth pattern and sharply circumscribed margins compared with classic chordomas.

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Extraosseous spinal chordoma in: Journal of Neurosurgery Volume 75 Issue 6 Year

In a recent article, Kurokawa, et al. Neuroradiology link – Pubmed citation. Extent of tumour and contrast enhancement: The evidence for this is the location of the cprdoma along the neuraxisthe similar immunohistochemical staining patterns, and the demonstration that notochordal cells are preferentially left behind in the clivus and sacrococcygeal regions when the remainder of the notochord regresses during fetal cordoja.

Gamma knife radiosurgery for remnant tumor was performed on 1 month after operation. Computerized tomography scan at the L-2 interspace demonstrating a focal disc herniation on the right arrow. Typically the mass projects posteriorly at midline, indenting the pons; this characteristic appearance has been termed the so-called thumb sign.

They most commonly involve cervical particularly C2followed by lumbar, and then the thoracic spine. The MR appearance of our patient’s tumor was dissimilar to that of true vertebral chordomas because of its extraosseous location.

For tumor control, conventional radiotherapy needs very high doses of radiation. Back pain was ascribed to both the extruded disc and the mass effect of the epidural lesion.

MRI drl, however, limited in its ability to evaluate calcification and the precise involvement of skull base osteolysis less well than CT, especially for skull base foramina. The position of the tumor at L-3 and the friability of the tumor tissue resulted in piecemeal removal. Benign bone erosion with sclerotic borders can be seen arrowindicating a long-standing erosive, rather than destructive, process.


Traditionally, surgical resection has been the first line of treatment when feasible, with radiotherapy offered for recurrent cases. The role of radiosurgery in the management of chordoma and chondrosarcoma of the cranial base.

Therefore, highly focused radiation such as proton therapy and carbon ion therapy are more effective than conventional x-ray radiation. Postoperative course The patient complained dizziness, but other symptoms, such as ataxia, right facial numbness without paralysis, right hearing disturbance, were much more cordma.

Rest of operation was uneventful. These tumours are often poorly marginated and microscopic distal extension of tumor cells likely explains the frequency of recurrences. Based on our morphological and immunohistochemical studies, we propose corddoma the tumor presented in this report, a bona fide intraspinal extraosseous extradural chordoma, had its origin in an ectopic notochordal remnant.

After near total resection of tumor Fig. MR imaging, performed 14months after gamma knife radiosurgery, revealed decreased size of remnant tumor compared with one before gamma knife radiosurgery Fig. Their illustration demonstrates a chondroid tumor-like nodule that differs histologically from cranial ecchordosis.

A purported example with unusual light microscopic features was reported by Maesen, et al.

Chordomas can arise from bone in the skull base and anywhere along the spine. Postoperative brain CT demonstrates no definite contrast enhancing mass in right cerebellopontine angle region and no bony destruction. Immunohistochemical stains showing expression of cytokeratin Band S protein C. Definitive radiation therapy for chordoma and chondrosarcoma of base of skull and cervical spine.

Intradural chordoma without bone involvement: From Wikipedia, the free encyclopedia. Case Report This previously healthy year-old woman presented with a 2-month history of lumbar, right sacroiliac joint, and right thigh pain.

Intradural Retroclival Chordoma

Find articles by Yeon Soo Choo. Report of flivus cases. Although the histological, immunocytochemical, and ultrastructural features of this tumor are those of ordinary cranial, vertebral, or sacral chordoma, the tumor described in this report exhibits a different topography and growth pattern, being extraosseous and confined to the epidural space.


Photomicrographs of the tumor specimen.

Support Radiopaedia and see fewer ads. The patient made an uneventful postoperative recovery and was ambulating in a cast brace. Most patients with skull base chordomas have been treated with a combination of surgery and radiotherapy, although the efficacy of cordoam is controversial It is of interest that the MR image in our case failed to delineate the right-sided disc herniation.

Chordoma is a rare slow-growing neoplasm thought to arise from cellular remnants cordkma the notochord. Fluid and gelatinous mucoid substance associated with recent and old hemorrhage and necrotic areas are found within these tumours. In some patients, calcification and sequestered bone fragments are found as well.

This page was last edited on 14 Novemberat Extraosseous processes that histologically resemble a chordoma include ecchordosis physaliphora 14, 17, 22, 25 and intradural chordoma. Primary intradural pontocerebellar chordoma metastasizing in the subarachnoid spinal canal. Radiographic Features Although the histological, immunocytochemical, and ultrastructural features of this tumor are those of ordinary cranial, vertebral, or sacral chordoma, the tumor described in clivhs report exhibits a different topography and growth pattern, being extraosseous and confined to the epidural space.

Extraosseous spinal chordoma

Chordomas are found along the axial skeleton and a relatively evenly distributed among three locations:. A portion of the tumor with sheet-like growth of vacuolated cells. Retrieved from ” https: Chordomas are rare tumors of central nervous system about 0. Radiological investigations included magnetic resonance MR imaging with gadolinium enhancement of the dek region and an iopamidol myelogram with computerized tomography CT of the lower four lumbar vertebrae.